RHYTHM PHARMACEUTICALS, INC. 10-K Cybersecurity GRC - 2026-02-26

Page last updated on February 26, 2026

RHYTHM PHARMACEUTICALS, INC. reported their cybersecurity risk management and governance process in a yearly 10-K filed on 2026-02-26 17:02:04 EST.

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10-K filed on 2026-02-26

RHYTHM PHARMACEUTICALS, INC. filed a 10-K at 2026-02-26 17:02:04 EST
Accession Number: 0001628280-26-012399

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Item 1C. Cybersecurity.

Item 1C. Cybersecurity Cybersecurity Risk Management and Strategy We have developed and implemented a cybersecurity risk management program intended to protect the confidentiality, integrity, and availability of our critical systems and information. 107 Table of Conten ts We design and assess our cybersecurity program based on the NIST Cybersecurity Framework (CSF). This framework provides us with a common language and structure for identifying, assessing, and managing cybersecurity risks across our organization. We do not claim to comply with the standards or specifications by using this framework. It is a guide to help us manage the cybersecurity risks that are relevant to our business. Our cybersecurity program is integrated into our overall enterprise risk management program, and shares common methodologies, reporting channels and governance processes that apply across the enterprise risk management program to other legal, compliance, strategic, operational, and financial risk areas. To this end, we have implemented a cybersecurity program that includes, but is not limited to, the following key elements: - Governance : The Board of Directors oversees our cybersecurity risk management strategy, regularly reviewing threats, risks, and mitigation measures. These reviews include both internal and independent evaluations of risks, controls, and effectiveness. - Vigilance : Our global cybersecurity operations are designed to detect, prevent, contain, and respond to cyber threats and incidents, aiming to minimize business disruptions. - Safeguards : We use administrative, technical, and physical controls designed to secure our personnel, information systems, operations, and sensitive data from cyber threats, such as cybersecurity policies and procedures, risk assessments, cybersecurity training, secure facility access, surveillance systems, firewalls, intrusion detection and prevention systems, disaster recovery capabilities, malware and ransomware defenses, access controls, and data protection. - Education : Personnel receive periodic cybersecurity training. Our policies require employees to report any actual or suspected cybersecurity events. - Third Party Risk Management : We strive to apply our cybersecurity standards to our third-party ecosystem, identifying and managing risks posed by third parties. - Incident Response : We have established an incident response plan that guides how we handle cybersecurity events and incidents. This plan includes procedures to detect, analyze, contain, and eradicate threats, and communicate significant incidents to executive management, the Board of Directors, regulators, and shareholders when appropriate. - Enterprise-Wide Coordination : Relevant stakeholders across the company-such as R&D, commercial, technology, legal, compliance, and other departments-work together to identify emerging risks and respond to cybersecurity threats through a cross-functional approach. - External Service Providers : We use external service providers, where appropriate, to assess, test, or otherwise assist with aspects of our cybersecurity processes. We have not identified any cybersecurity incidents that have materially affected our operations, business strategy, results of operations, or financial condition. We face risks from cybersecurity threats that, if realized, are reasonably likely to materially affect us, including our operations, business strategy, results of operations, or financial condition. For more information, see the section titled "Risk Factors- Our information technology systems, or those of our third-party CROs, CMOs or other contractors or consultants, may fail or suffer security breaches, which could result in a material disruption of setmelanotide development programs, regulatory investigations, enforcement actions and lawsuits." Cybersecurity Governance Our Board considers oversight of cybersecurity risk to be an essential component of its enterprise risk oversight responsibility and directly oversees management's implementation of our cybersecurity program. The Board receives periodic reports from management on our cybersecurity program and risks. In addition, management updates the Board, where it deems appropriate, regarding any cybersecurity incidents it considers to be significant. Board members receive presentations on cybersecurity risk and strategy from our Cybersecurity Director, as part of the Board's continuing education on topics that impact public companies. The Cybersecurity Director, with the help of our IT and Legal team is responsible for assessing and managing our material risks from cybersecurity threats. This position has the primary responsibility for our overall cybersecurity risk management program and supervises both our internal personnel and our retained external cybersecurity consultants. The current Cybersecurity Director has extensive information security and program management experience and has held past positions as the head of cybersecurity for a wide range of organizations. 108 Table of Conten ts Our management team supervises efforts to prevent, detect, mitigate, and remediate cybersecurity risks and incidents through various means, which may include briefings from internal security personnel and other information obtained from governmental, public, or private sources, including external consultants engaged by us, and alerts and reports produced by security tools deployed in the IT environment.

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